#CGAIGC24

Scientific Program

Legend	Scientific Sessions
	Industry Symposium
	Abstract Sessions

Session Time	Sessions
07:00 – 07:45
08:00 – 08:10	Welcome & Housekeeping *Bryson Katona, CGA-IGC President*
08:10 – 09:55	Session I: Genetic Counseling Conundrums Moderators: Zach Foda & Michelle Savage McSweeny Genetic counseling and genetic testing challenges at the end of life, Lisa Madlensky Q&A Germline genetic testing and transplant eligibility, Katie Lang Q&A Impact and implications of variant reclassification in cancer genetics, Sukh Makhnoon Q&A How We Do It – Mainstreaming Genetic Testing for CRC Patients, Matthew F Kalady & Josie Baker & Kathryn Baker
09:55 – 10:15	Break
10:15 – 11:15	Debate: Pancreatic Cancer Early Detection Debate: BRCA1/2, PALB2, ATM carriers without a family history of pancreatic cancer: To screen or not to screen the pancreas? Moderators: Dana Zakalik & Shenin Sanoba Yes, Aimee Lucas No, Randy Brand Rebuttals and Q&A
11:15 – 12:15	Named Lecture: Lemuel Herrera Lecture Moderator: Hannah Campbell & Michelle Springer Introduction, Hannah Campbell Diversity in Genetic Counseling, Erica Ramos Q&A Reflections From A Patient And Research Advocate, Wenora Johnson Q&A
12:15 – 13:45	LUNCH BREAK
13:45 – 15:15	Presidential Plenary I Moderators: Peter Stanich & Bryson Katona Trends in Lifespan and Cause of Death Among Patients with Familial Adenomatous Polyposis, *Brian Christopher Brajcich* Reproductive Decision Making and Maternal and Fetal Risk in Individuals with Germline {CDH1} Variants, Cassidy Rose Bowden Gastric and lobular breast cancer prevalence in {CTNNA1} heterozygotes identified via multigene panel testing, Jennifer Herrera Mullar Clinicopathologic and allele-specific analysis of germline and somatic MUTYH alterations in a pan-cancer cohort, Matteo Repetto Outcomes of Intestinal Transplantation for Familial Adenomatous Polyposis Associated Intraabdominal Desmoid Disease, Mohamed Elshawy Predictors of Invasive Signet Ring Cell Carcinoma in {CDH1} Carriers – Results from the GASTRIC Consortiumact, Ophir Gilad
15:15 – 16:00	PM Break
15:25 – 15:55	CCARE Lynch Syndrome Poster Walk Moderators: Zsofia Stadler & Megha Ranganathan Small Bowel Surveillance Assessed by Video Capsule Endoscopy in Asymptomatic Lynch Syndrome Subjects, Giulia Martina Cavestro Genotype Specific Lynch Associated Cancer Risk Compared to the General Population: Results from a Nationwide Database, Timothy Yen Endometrial Intraepithelial Neoplasia (EIN) as a Precursor in Lynch Syndrome-Associated Endometrial Carcinoma, Hadley Reid Efficacy of Urinary Tract Cancer Surveillance Among Patients with Lynch Syndrome, Mehul Trivedi Immunogenic Profiles in Lynch Syndrome Colorectal Cancers are Consistent Across Different Mismatch Repair Gene Defects, *Noah Cornelis Helderman*
16:00 – 17:00	Named Lecture: Henry Lynch Lecture Moderators: Jacquelyn Powers & Dan Li Introduction, Jacquelyn Powers Cancer risk management and interception opportunities in BRCA1/2 carriers, Susan Domchek Q&A Assessment of Pancreatic Cancer Screening in High-Risk Patients: Experience from a Community Health System, Jacqueline Neminski Outcomes of Risk Assessment and Genetic Testing for Patients with Early-onset Adenomas, W. Curtis Weaver A Blood-based, Multiplex Protein Biomarker Signature Shows Superior Performance in Detection of Early-stage Pancreatic Ductal Adenocarcinoma (PDAC), Norma Palma Peutz-Jeghers Syndrome and Lung Cancer Risk: Does the Risk Meet the Threshold for Lung Cancer Screening?, Jennifer M. Weiss Insurance Coverage and Denials of Guideline-Recommended Colorectal Cancer Genetic Testing, Edward Esplin
17:00- 18:00	Hereditary Live Moderator: Joshua Sommovilla Panelists: Swati Patel, Matthew Yurgelun, Jessica Long Case Presentation 1, *Ophir Gilad & Christine Drogan* Case Presentation 2, Asaf Maoz
18:00 – 19:00	Poster Session 1
20:00 – 22:30	Social Session

Session Time	Sessions
07:00 – 07:45	Sponsored Breakfast
12:30 – 13:30	Sponsored Lunch

Session Time	Sessions
07:00 – 07:45
08:00 – 08:10	Welcome & Housekeeping *Bryson Katona, CGA-IGC President*
08:10 – 09:40	Session II: Lynch syndrome Moderators: Mohammad Abbass & Veroushka Ballester Gynecologic controversies in Lynch syndrome: utility of screening, contraceptive use, and surgical timing and extent, Lee-May Chen Q&A Segmental colectomy is the preferred surgical approach in Lynch syndrome, Carlos Vaccaro Extended colectomy is the preferred surgical approach in Lynch syndrome, Jose Guillem Rebuttals and Q&A
09:40 – 10:00	AM Break
10:00 – 10:45	Named Lecture: Jeremy Jass Lecture Moderators: Sanjeevani Arora & Aparajita Singh Introduction, Sanjeevani Arora 25 years of CDH1: history, current controversies, and future opportunities, Jeremy Davis Q&A
10:45 – 12:00	Session III: International Updates Moderators: Pooja Dharwadkar & Tatiana Johnson Updates from the 2024 IGCLC Meeting, Carla Oliveira, Portugal Q&A Updates from the 2024 Insight Annual Meeting, Francesc Balaguer, Spain Q&A Comprehensive characterization of screening strategies for Lynch syndrome from a large cohort of colorectal cancer individuals of Latin American, Mev Dominguez Valentin, Norway
12:00 – 13:20	LUNCH BREAK
13:20 – 14:50	Presidential Plenary II Moderators: Bryson Katona & Beth Dudley Development And Validation Of An Exosome-Based And Machine Learning Powered Liquid Biopsy For Early-Onset Colorectal Cancer: The {ENCODE} Study, Alessandro Mannucci “It would just make everything easier”: Patient perspectives on the potential of mHealth to reduce the burden of care management in Lynch syndrome, Jordan Clawson Parent-of-origin assignment of pathogenic variants without parental data, Kasmintan A Schrader Influence of Preoperative Lynch Syndrome Diagnosis on the Extent of Surgery in Patients with Colon Cancer, Mohammad Ali Abbass Modeling uptake of aspirin (ASA) and NSAIDS in Lynch syndrome (LS) to elucidate barriers to chemoprevention of hereditary cancers, Michael Hall Risks of Colorectal Cancer Among TP53 Mutation Carriers in the LiFT-UP Study, Stephen B Gruber
14:50 – 15:10	PM Break
15:10 – 16:55	Session IV: Polyposis Moderators: Douglas Riegert-Johnson and Julie Moskowitz Thyroid cancer risk and surveillance across hereditary polyposis syndromes, Steven Waguespack Q&A Juvenile polyposis syndrome with and without a driver gene mutation: Same syndrome different phenotypes or different syndromes?, Suzanne MacFarland Q&A Emerging polyposis syndromes: risks and management both within and outside the colon, Melyssa Aronson Q&A How We Do It: Management of complex upper gastrointestinal lesions in FAP: selection, technical considerations, benefits, and limitations, Carol Burke & Amit Bhatt & Michael Cruise
17:00 – 18:00	Jeopardy Moderators: Michael Hall & Maegan Roberts Hereditary or not, Here We Come, Eve Karloski, Paul Wise, Carol Burke The Mismatch Mavericks, Timothy Yen, Alicia Latham, Kimberly Hilfrank CHEK2 Yo Self, Jill Genua, Greg Idos,Catherine Neumann
18:00 – 19:00	Poster Session 2

Session Time	Sessions
07:00 – 07:45	Sponsored Breakfast
12:10 – 13:10	Sponsored Lunch

Session Time	Sessions
07:00 – 07:45
08:00 – 08:10	Welcome & Housekeeping *Bryson Katona, CGA-IGC President*
08:10 – 10:10	Session V: Hot Topics in Hereditary GI Cancer Moderators: Gautam Mankaney & Kristin Zelley Hepatobiliary cancers: germline genetic associations and when to test, Kirk Wangensteen Q&A Gastrointestinal cancer risks and management in Li-Fraumeni syndrome, Kara Maxwell Q&A Care for transgender individuals with a hereditary GI cancer Syndrome, Rachel Hodan Q&A Genetic discrimination: Updates and implications for genetic counseling, Jennifer Wagner Q&A
10:10 – 10:30	AM Break
10:30 – 11:30	Session VI: Pancreatic Cancer Early Detection Moderators: Lisen Axell & Joel Gabre MRI for pancreatic cancer screening: pros, cons, and other considerations, Carla Harmath Q&A Blood-based tests for pancreatic cancer screening in high-risk individuals: What should be used and how?, Fay Kastrinos Q&A
11:30 – 12:15	Named Lecture: Bert Vogelstein Lecture Moderators: Jennifer Weiss & Daniel Luba Introduction, *Jennifer Weiss* Non-invasive colorectal cancer screening and the potential application to hereditary GI cancer syndromes, Aasma Shaukat Q&A
12:15 – 13:45	LUNCH BREAK
13:45 – 15:15	Presidential Plenary III Moderators: Beth Dudley & Elana Levinson The Incidence of Pancreatic Cancer in Women with a BRCA1 or BRCA2 mutation, Bryson W Katona The At-Risk Cancer Genetic Syndrome Identification (ARCAGEN-ID) project: A systems approach to scale-up Lynch syndrome identification, Xavier Llor Development of a Clinical Decision Support Tool for Cancer Risk Assessment for Trans and Gender-Diverse Patients with Lynch Syndrome, Joyce Gong Predictors of Positive Genetic Testing in Adenomatous Polyposis, Peter P Stanich Patient preferences for selective exclusion of high-risk genes on multigene panel testing, Samuel Levy Impact of RNA Sequencing on Variant Classification: Experience at a High-Volume Cancer Genetics Center, *Sydney Rudowski*
15:15 – 16:15	CGA-IGC Business Meeting & Presidential Transition Bryson Katona & Michael Hall Post Meeting Wrap Up Beth Dudley

Session Time	Sessions
07:00 – 07:45	Sponsored Breakfast
12:30 – 13:30	Sponsored Lunch

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